Advanced CMOS based Biomedical Sensing Devices

The advances of CMOS technology in the past decades have paved the way for smart sensing devices. Current CMOS based imagers have remarkable performance and are available for utilization in fully integrated compact sensing systems.  A high sensitivity, wide dynamic range image sensor is the basis for several advanced biomedical sensing devices described herein. Custom optical filter coatings are designed to serve different substances detection. The first is a system detecting Calcium, enabling a portable, low cost system for neuron monitoring. The different parameters affecting the filter fabrication process are explained. We follow up with additional filter coatings suitable for other applications. One, for water quality monitoring, is based on chlorophyll detection. Another, serving the same purpose, is for color dissolved organic matter (CDOM) detection. An optical based pH detection system is also described and further developments in process are reviewed.